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CACN-1/Cactin Plays a Role in Wnt Signaling in C. elegans

Figure 9

cacn-1 RNAi alters the asymmetrical localization of GFP::POP-1 in seam cells.

sys-1p::GFP::POP-1 animals were grown on E. coli HT115(DE3) carrying (A) control RNAi or (B) cacn-1 RNAi vector. White lines indicate V3.pp(a/p), V4.pa(a/p) and V4.pp(a/p) seam cell daughters. In cacn-1 animals the asterisks indicate equal POP-1 in both daughter cells of V4.pa(a/p) and V4.pp(a/p) divisions. Scale bar is 20 µm. (C) Individual points represent the posterior/anterior ratio of GFP expression in each seam cell pair for a given RNAi treatment. * indicates statistical significance of P = 0.011.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0101945.g009