Methylseleninic Acid Sensitizes Notch3-Activated OVCA429 Ovarian Cancer Cells to Carboplatin
Figure 2
The effect of NAC on the sensitivity of OVCA429/pCEG and OVCA429/NICD3 cells to MSeA and carboplatin co-treatment.
OVCA429/pCEG (A, C) and OVCA429/NICD3 (B, D) cells were treated with MSeA and a gradient concentration of carboplatin (A, B) or carboplatin and a gradient concentration of MSeA (C, D) in the presence or absence of NAC. Cell viability was determined by SRB assay. Viability of the cells without carboplatin (A, B) or MSeA (C, D) treatment was set as 100%. Values are mean ± S.E.M. (n = 3). *, p < 0.05, compared to MSeA or carboplatin only treatment.