Magnetic Resonance Colonography for Fibrosis Assessment in Rats with Chronic Colitis
Figure 3
Association between MRC criteria and colon COX-2 expression in rats with chronic colitis.
Chronic colitis was induced in rats by intrarectal injection of TNBS repeated on a weekly basis from day 0 to day 35. MRC was performed at day 42. Maximal and minimal thickness, colon wall signal intensity and luminal narrowing was measured on MR images. Colon COX-2 expression was measured by western blot. Simple linear regression between maximal (A°, minimal (B), colon wall signal intensity (C), luminal narrowing (D) and COX-2 expression. score. Pearson correlation was performed.