Bovine Collagen Peptides Compounds Promote the Proliferation and Differentiation of MC3T3-E1 Pre-Osteoblasts
Figure 3
Real-time-PCR analysis of the expressions levels of different osteoblast markers after bovine CP compound treatment.
Real-time PCR analyses of the Runx2 (A), ALP (B), Col1α1 (C), and OC (D) mRNA levels in MC3T3-E1 cells induced with osteogenic medium after treatment with 3 mg/mL CP or no treatment (CN) for 7 or 14 days are shown. The results were normalized by the mRNA levels of β-actin as a housekeeping gene. Data are expressed as means ± standard deviation (n = 4). *p<0.05, **p<0.01, Significant difference from CN. CP: bovine collagen peptides compounds; CN: control.