The ARL2 GTPase Is Required for Mitochondrial Morphology, Motility, and Maintenance of ATP Levels
Figure 5
Microtubules are not lost with expression of ARL2[K71R] or ARL2 siRNA.
HeLa cells were transfected with plasmids directing expression of ARL2, ARL2[T30N], ARL2[K71R], ARL2[Q70L], or with ARL2 siRNA #1. Cells were fixed 48 hours later and stained for α-tubulin, as described under Materials and Methods. Representative confocal images are shown, though the extent of microtubule density loss with ARL2[T30N] and ARL2[Q70L] vary and is more severe with the latter.