PTK6 Promotes Cancer Migration and Invasion in Pancreatic Cancer Cells Dependent on ERK Signaling
Figure 1
PTK6 is expressed in pancreatic cancer cell lines and human pancreatic adenocarcinoma tissues at various levels.
A, Endogenous expression of PTK6 in human pancreatic cancer cell lines. PTK6 expression was confirmed in 5 pancreatic cancer cell lines, BXPC3, Capan1, Hs766T, MIAPaCa2, and Panc1 at various levels by Western-blotting. B, Immunohistochemical staning for PTK6 in adjacent normal pancreas and pancreatic cancer tissue. While there was no detectable PTK expression in adjacent normal pancreatic ductal epithelium (upper left), PTK6 was expressed at various levels (from negative through strongly positive) in pancreatic cancers.