Multiscale Complexity Analysis of the Cardiac Control Identifies Asymptomatic and Symptomatic Patients in Long QT Syndrome Type 1
Figure 4
RMSE at long time scales over HP and QT series.
RMSE mean (plus standard deviation) assessed at long time scales (i.e. τ = 5–12) over HP series, RMSEHP,τ = 5–12 (a,c,e), and QT series, RMSEQT,τ = 5–12 (b,d,f), is shown as a function of the experimental protocol. RMSEHP,τ = 5–12 and RMSEQT,τ = 5–12 are depicted as a function of the group of subjects in the NMC-MC protocol in (a) and (b) respectively, as a function of the period of analysis in the DAY-NIGHT protocol in (c) and (d) respectively, and as a function of the therapy in the BBoff-BBon protocol in (e) and (f) respectively. The gray, dark and white bars are relevant to NMC, ASYMP and SYMP individuals, respectively. The symbol * indicates a significant difference between experimental conditions (i.e. DAY versus NIGHT, BBoff versus BBon) within the same group with p<0.05. The symbol # indicates a significant difference between groups within the same experimental conditions (i.e. DAY, NIGHT, BBoff or BBon) with p<0.05.