Antifungal Activity of Naphthoquinoidal Compounds In Vitro against Fluconazole-Resistant Strains of Different Candida Species: A Special Emphasis on Mechanisms of Action on Candida tropicalis
Figure 5
An evaluation of ROS formation in fluconazole-sensitive (A) and fluconazole-resistant (B) C. tropicalis isolates after treatment with naphthofuranquinone (NFQ) compounds 1, 2 and 3 using the concentrations 32 µg/mL (a); 64 µg/mL (b) and 128 µg/mL (c).
The percentage of ROS formation in the fluconazole-sensitive and fluconazole-resistant C. tropicalis isolates was evaluated for 24 hours. * P<0.05 compared with the control using an ANOVA followed by the Newman-Keuls test.