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Changes in Positive End-Expiratory Pressure Alter the Distribution of Ventilation within the Lung Immediately after Birth in Newborn Rabbits

Figure 5

Changes in VT and FRC during decreasing PEEP.

The increase in tidal volume (VT) and decrease in functional residual capacity (FRC) when positive end-expiratory pressure (PEEP) is decreased in 5 cmH2O stepwise decrements (10-5-0PEEP), large steps (10-0PEEP) and from a small step (5-0PEEP) in the ventilated lung. Asterisks (*) indicate that values during 5-0PEEP are significantly different to their corresponding quadrant during 10-5-0PEEP and 10-0PEEP. Double asterisks (**) indicate that values during 10-5-0PEEP are significantly different to their corresponding quadrant during 10-0PEEP. Daggers (†) indicate that values during 5-0PEEP are significantly different to their corresponding quadrant during 10-0PEEP. Values are significantly different if p<0.05. There was no significant difference between quadrants within any group.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0093391.g005