Apraxia and Motor Dysfunction in Corticobasal Syndrome
Figure 3
Voxel-based morphometry analysis demonstrating brain regions that positively correlate with neurophysiological parameters in CBS patients.
(A) Reduced RMT correlated with atrophy of the primary motor cortex (red circles), thalamus (blue circle) and the anterior temporal lobe (magenta circle). (B) Reduced SICI correlated with atrophy of the primary motor cortex (red circle), thalamus (blue circles), medial frontal cortex (yellow circles) and precuneus (green circles). Clusters are overlaid on the Montreal Neurological Institute standard brain (t>2.41). Colored voxels show regions that were significant in the analyses for P<0.001 uncorrected and a cluster threshold of 20 contiguous voxels. Circled areas indicate: red = primary motor cortex; blue = thalamus; magenta = anterior temporal lobe; yellow = medial frontal cortex; green = precuneus.