Integrative ChIP-seq/Microarray Analysis Identifies a CTNNB1 Target Signature Enriched in Intestinal Stem Cells and Colon Cancer
Figure 4
Validation of CTNNB1 direct target genes.
A. ChIP-PCR analysis of the indicated genes using an independently prepared chromatin sample. LEF1 and GAPDH serve as positive and negative controls, respectively. B. Quantitative RT-PCR of the indicated genes. Mean ± standard deviation of 4 independent experiments are shown. p values are calculated with two-tailed standard t-test. N.S.: not significant, *: p<0.05, and **: p<0.01.