Resveratrol as a Natural Anti-Tumor Necrosis Factor-α Molecule: Implications to Dendritic Cells and Their Crosstalk with Mesenchymal Stromal Cells
Figure 6
Presence of resveratrol rescues MSC motility in co-cultures with DC.
DC were differentiated and stimulated as indicated, before being added to MSC cultures (1MSC:10DC). The cultures were followed by time-lapse video-microscopy for 12 h. Image analysis was performed using ImageJ software. A. Images with representative pathways from cell tracking using ImageJ. Examples of MSC (red) and DC (yellow) tracks are highlighted. Scale bar: 100 µm. B. Quantification of MSC and DC travelling distance when cultured together, versus separately. Box&Whiskers plots represent median (dash) and range of values. Statistical significance was calculated using Mann-Whitney test (*p<0.05, **p<0.01, ***p<0.001).