Increased Actin Polymerization and Stabilization Interferes with Neuronal Function and Survival in the AMPKγ Mutant Loechrig
Figure 10
loe flies show progressive neuritic degeneration.
A. Expression of GFP via pdf-GAL4 reveals the pattern of the PDF neurons and their projections into the medulla (arrowheads) in a 5 d old control fly. B. In a 1 d old loe fly, the overall pattern appears quite normal although the staining of the projections into the medulla appears somewhat weaker. C. In a 5 d old loe fly the arborizations in the medulla are thin or missing whereas the cell bodies are still easily detectable (arrow). Scale bar in A = 10 µm also applies to B and C).