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V3-Independent Competitive Resistance of a Dual-X4 HIV-1 to the CXCR4 Inhibitor AMD3100

Figure 4

Susceptibilities of replication-competent recombinant viruses.

SupT1/CCR5 cells were infected with the same amount of replication-competent recombinant viruses carrying mutations (100 TCID50) in the presence of various concentrations of AMD3100, and then cultured for 6 days. Cytopathic effects were determined by an MTT assay. Data are the means ± SD of triplicate experiments.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0089515.g004