Parental Binge Alcohol Abuse Alters F1 Generation Hypothalamic Gene Expression in the Absence of Direct Fetal Alcohol Exposure
Figure 5
Effects of parental adolescent binge EtOH exposure on the expression of hypothalamic genes involved in transcription and translational regulation in the hypothalamus of PND 7 male and female offspring.
qRT-PCR analysis of Egr2 (A), DICER1 (B), Wbp4 (C) and SUMO2 (D) mRNA expression in the hypothalamus of PND 7 male and female pups from water- or binge EtOH - treated parents (white and black bars, respectively). Data are expressed as mean ± SEM of mRNA fold change in relation to control pups from water- treated parents. (*) indicates a statistically significant difference from control (p<0.05).