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E. coli Infection Modulates the Pharmacokinetics of Oral Enrofloxacin by Targeting P-Glycoprotein in Small Intestine and CYP450 3A in Liver and Kidney of Broilers

Figure 3

Immunohistochemical staining of P-glycoprotein in different tissues of healthy and E. coli infected broilers.

Mouse monoclonal anti-P-gp antibody (C219) was used to detect P-gp. These figures are representatives of typical samples from 5 broilers in each group. The arrow showed the positive staining of P-gp. Magnifications are indicated by bar.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0087781.g003