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Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease

Figure 1

Prevalence of significant fibrosis according to GCKR rs780094 SNP in the Sicilian cohort, in the Center/Northern Italian cohort, and in the combined cohorts of NAFLD patients.

*p = 0.02 for prevalence of F2–F4 fibrosis according to GCKR genotype; ° p = 0.04 for prevalence of F2–F4 fibrosis according to GCKR genotype; ∧p = 0.001 for prevalence of F2–F4 fibrosis according to GCKR genotype.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0087523.g001