Effects of an Anticarcinogenic Bowman-Birk Protease Inhibitor on Purified 20S Proteasome and MCF-7 Breast Cancer Cells
Figure 5
Inhibitory activity of BTCI and MG132 (positive control), toward 20S proteasome caspase-like (Casp), chymotrypsin-like (Chym) and trypsin-like (Tryp).
The concentration of both inhibitors is 10 µM. As shown, BTCI is a more potent inhibitor for trypsin than MG132 and presented similar inhibition to MG132 against caspase-like and chymotrypsin-like.