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Oral Administration of Lactobacillus plantarum Strain AYA Enhances IgA Secretion and Provides Survival Protection against Influenza Virus Infection in Mice

Figure 1

IgA production induced by PP cells.

(A) PP cells (1×106/well) from BALB/c mice fed a normal diet (AIN93G), and each LABs were co-cultured. Supernatants were harvested after 7 days, and IgA concentrations were measured by ELISA. Data are shown as mean ± SE. n = 5. Data represent one of two similar experiments. (B) PP cells (1×106 per well) from BALB/c mice fed the diet containing LAB were incubated. Supernatants were harvested, and IgA concentrations were measured by ELISA after 7 days. Data are shown as mean ± SE. n = 5. Asterisk indicate unpaired Student’s t test; P value is <0.05. Data represent one of two similar experiments.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0086416.g001