IFNα Serum Levels Are Associated with Endothelial Progenitor Cells Imbalance and Disease Features in Rheumatoid Arthritis Patients
Figure 4
Cytokine profiles and disease features in RA patients are dependent on IFNα serum levels.
(A) Proinflammatory cytokines are increased in IFNhigh patients compared with both HC and IFNlow patients. (B) Serum cytokines levels are restored in IFNlow-treated patients but not in IFNhigh ones. (C) Improvement in clinical parameters in IFNlow-treated patients compared with IFNhigh group. Differences between groups were assessed by Mann-Withney U-test. n. t.: non-treated; t.: treated. *p<0.05, **p<0.01, ***p<0.001.