The Leukotriene B4/BLT1 Axis Is a Key Determinant in Susceptibility and Resistance to Histoplasmosis
Figure 2
Differential leukocyte recruitment to the lung in resistant (129/Sv) and susceptible (C57BL/6) mice.
Cells were obtained from mice at 7 and 14 days after i.t. injection of PBS or 5×105 H. capsulatum yeast cells, as described in the Materials and Methods section. The total cells (A), neutrophils (B) and mononuclear cells (C) were enumerated and identified after Rosenfeld staining. The data are expressed as the mean ± SEM from one representative experiment of a total of three experiments (n = 6/each experiment). *C57BL/6 and sv129 compared with PBS; #C57BL/6 compared with sv129. p<0.05 was considered significant.