Mapping the Kinetic Barriers of a Large RNA Molecule's Folding Landscape
Figure 5
Eyring analysis of the reactions for the structural-kinetic model as depicted in Figure 4A.
Values for ΔH‡, ΔS‡ and ΔG‡ are summarized in Table 2. (A) Eyring plots were fit to the Eyring equation (eq. 1). Eyring plots for the primary transitions U → I1 (full circles), U → I2 (empty square) and secondary transitions I1 → F (solid triangles), I2 → F (empty triangles) are shown. (B) Temperature dependence of ΔG‡. ΔG‡ values are derived by solving eq. 4 and fitted linearly; U → I1 (full circles), U → I2 (open squares), I1 → F (solid triangles) and I2 → F (open triangles).