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Aberrant Neural Stem Cell Proliferation and Increased Adult Neurogenesis in Mice Lacking Chromatin Protein HMGB2

Figure 2

Heightened DCX expression in the SVZ of 10 week old Hmgb2−/− mice.

Mash1 and Nestin expression in lateral Hmgb2+/+ and Hmgb2−/− brain sections and surface plots of pixel density distributions (A,B). Doublecortin (DCX) in lateral and medial Hmgb2+/+ and Hmgb2−/− brain sections (C,D) with quantification of DCX+ cells/SVZ hpf in WT and Hmgb2−/− medial brain sections (E). The values are mean+/− SEM, **p = 0.036.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0084838.g002