Reconstructed Ancestral Myo-Inositol-3-Phosphate Synthases Indicate That Ancestors of the Thermococcales and Thermotoga Species Were More Thermophilic than Their Descendants
Figure 2
Comparison of amino acid compositions between Thermococcus sequences and Thermotoga sequences.
The y-axis is amino acid (AA) counts and the x-axis is the amino acid. Red bars are the mean of the extant Thermotoga sequences; white, yellow, green and orange bars are the Thermotoga ancestral reconstructed sequences ATM_T1–T4, respectively. Dark blue bars are the mean archaeal sequences, and pink and light blue bars are the Thermococcus ancestral reconstructed sequences ACM_C1–C2, respectively. A (*) marks where there is a significant difference (p<0.01) in the AA counts between the Archaea and the Thermotoga. A (#) marks where there is a significant difference between the extant Thermotoga sequences and the reconstructed Thermotoga sequences. This shows there is no significant difference between the Thermococcus extant sequences and the Thermococcus ASR sequences, see Table S4 for p-values.