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Mice Lacking NMDA Receptors in Parvalbumin Neurons Display Normal Depression-Related Behavior and Response to Antidepressant Action of NMDAR Antagonists

Figure 3

Ketamine and MK801 do not affect locomotor activity behavior in the open field.

Time course for the locomotor activity of C57BL/6N mice in the 60 min before and 60 min after saline (black circles, n = 5), ketamine (gray circles, n = 6) and MK801 (white circles, n = 5) injection (arrow) (p>0.05, one way ANOVA).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0083879.g003