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Growth Pattern Analysis of Murine Lung Neoplasms by Advanced Semi-Automated Quantification of Micro-CT Images

Figure 6

Comparison of lung tumor growth measured manually by an observer and by the semi-automated algorithm.

Best linear fit growth curves were plotted for tumors from mouse 2 (left) and mouse 4 tumor A (right) based on measurements by a manual approximation method and by the semi-automated algorithm. The slopes of the best-fit lines for the manual and semi-automated measurements were compared by Student's t-test, and no significant differences were observed between the two slopes (P = 0.62 for mouse 2 and P = 0.57 for mouse 4 tumor A).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0083806.g006