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A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

Figure 16

Expression of enzymes involved in fatty acid oxidation.

Panel A: Hepatic expression of cyclooxygenases (COX1 & 2), lipoxygenases (5-. 12- & 15-LOX). Panel B: Hepatic expression of cytochrome P450-C2 (CYP2C subtypes) and soluble and microsomal epoxide hydroxylases (EPHX1 and 2). Results are represented as mRNA Abundance-Fold Change, mean ± SD; n=8/group; *, p ≤ 0.05 versus chow; #, p ≤ 0.05 versus WD + O.

Figure 16

doi: https://doi.org/10.1371/journal.pone.0083756.g016