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Impact of Pelvic Radiotherapy on Gut Microbiota of Gynecological Cancer Patients Revealed by Massive Pyrosequencing

Figure 2

Impact of radiation therapy on the gut microbial community.

Unique sequences, observed OTUs, estimated OTUs, and diversity indices (H) according to radiation therapy were analyzed (A). The mean number (± SEM) of each parameter is shown. P-values between T0 and T3 are marked. Changes of six major phylum-level taxa during radiation therapy are represented (B). The mean abundance (± SEM) is shown. P-values representing significant differences are only shown for each taxonomic group. T0 = before radiation therapy, T1 = after first radiation therapy, T2 = after fifth radiation therapy, and T3 = follow-up samples.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0082659.g002