The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy
Figure 1
PCR-RFLP to determine MDM2 SNP309 polymorphism.
MDM2 SNP309 T allele is not cleaved by MspA1I endonuclease and generates a single fragment of 155 bp. The MDM2 SNP309 G allele is cleaved by MspA1I and generates two small fragments of 101 and 54 bp. The MDM2 SNP309 heterozygote displays three fragments of 155, 101 and 54 bp.