Predicting the Activity Coefficients of Free-Solvent for Concentrated Globular Protein Solutions Using Independently Determined Physical Parameters
Figure 1
Activity Coefficient of Free-Solvent Using Literature Values of the Physical Parameters vs. Concentration for BSA in 0.15 M NaCl, pH 4.5.
The calculated activity coefficients of BSA in 0.15(closed circles) are shown. The predicted activity coefficients (Eqn. 12) are plotted using the physical parameters available in literature for BSA in 0.15 M NaCl, pH 4.5 ( mol NaCl/mol BSA [6]): g H2O/g BSA (solid curve) and g H2O/g BSA (dotted curve).