C. elegans Aging Is Modulated by Hydrogen Sulfide and the sulfhydrylase/cysteine Synthase cysl-2
Figure 2
The transcriptional response of wildtype exposed to GYY4137 and in cycl-2 mutants.
Genes involved in aging- and stress-related pathways were selected to evaluate, by qPCR, expression changes associated with GYY4137 treatment (A) in wild type C. elegans in the absence (-) or presence (+) of GYY4137 (100 µM) and (B) in cysl-2 mutants compared to N2 wild type (in the absence of GYY4137).