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Knockdown of SCFSkp2 Function Causes Double-Parked Accumulation in the Nucleus and DNA Re-Replication in Drosophila Plasmatocytes

Figure 4

Enlarged cells elicited by functional knockdown of lin19 exhibit increased nuclear BrdU staining.

(A,B) PxnGal4>w1118 wild-type animals were fed BrdU during larval stages resulting in slight incorporation into the DNA as visualized by anti-BrdU and DAPI staining. (C,D) pxnGal4>lin19 RNAiHM05197 were fed BrdU during laval stages resulting in a distinct nuclear BrdU staining in the nucleus when observed with DAPI staining. Scale bar = 20 μm.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0079019.g004