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Human Oral Isolate Lactobacillus fermentum AGR1487 Reduces Intestinal Barrier Integrity by Increasing the Turnover of Microtubules in Caco-2 Cells

Figure 2

Summary of the gene expression profiles of Caco-2 cells untreated or treated with L. fermentum AGR1485 and L. fermentum AGR1487 for 8 hours.

A Venn diagram showing the number of differentially expressed genes in each comparison. B Graph showing the Partial Least Squares Discriminant Analysis (PLS-DA) of the gene expression data. The dots represent the individual samples in each treatment group. C Heatmap showing the average expression levels of genes within KEGG pathways (indicated by row labels) significantly over-represented among differentially expressed genes between the L. fermentum AGR1485 and L. fermentum AGR1487 treated Caco-2 cells.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0078774.g002