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N-Acetylcysteine Prevents Spatial Memory Impairment Induced by Chronic Early Postnatal Glutaric Acid and Lipopolysaccharide in Rat Pups

Figure 4

Effect of early postnatal chronic GA, NAC and LPS administration on cytokine levels on the second day of Barnes maze.

NAC prevented the increase in TNF-α (A) and IL-1β (B) levels. *P < 0.001 compared with saline treated group, #P< 0.001 compared with the respective control group and δP < 0.05 compared with GA-treated group (Duncan’s multiple comparisons test). Data are presented as means ± S.E.M. for n = 6-7 in each group.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0078332.g004