A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse
Figure 5
Allelic series of Etv5 mouse models.
(A) The Etv5tmKmm mouse line carried a targeted deletion of exons 2–5. (B) Etv5tm1.2Xsun allele mouse line carried a targeted deletion of exons 10–11. (C) The Etv5tm1Hass mouse line carried a targeted deletion of exons 11–12 which were replaced with a LacZ-PGK-Neo cassette. (D) Etv5sco/sco mouse line contained an ENU-induced PTC-mutation in exon 12.