Natural Killer Cells from Patients with Chronic Rhinosinusitis Have Impaired Effector Functions
Figure 3
Patients with recalcitrant CRS have altered NK cell receptor expression patterns.
(A) Representative FACS profiles showing the expression of the CD16, NKG2C, NKG2D, 2B4, NKp46, KIR2DL1/S1, NKG2A and CD57 receptors (shaded histogram) on gated NK cells in normal donors (N), patients with recalcitrant CRS (RE-CRS), and patients with treatment-resistant CRS (TR-CRS). Isotype control staining is shown as solid lines. (B) Summary graphs of statistical dot plots showing the mean fluorescence intensity (MFI) of the indicated receptor expression on NK cells of the different study groups. Horizontal bars indicate the medians. *P<0.05.