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Characteristic and Functional Analysis of Toll-like Receptors (TLRs) in the lophotrocozoan, Crassostrea gigas, Reveals Ancient Origin of TLR-Mediated Innate Immunity

Figure 4

Subcellular localization of CgTLRs in HEK293 cells.

Empty plasmid pEGFP-N1was used as control. Red, green and blue colors show localization of Rab7-Red, the GFP tag or GFP-tagged CgTLRs and nucleus, respectively. Rab7-Red was a marker for late endosome. The four CgTLRs have similar intracellular localizations, majoring on late endosomes and minoring on plasma membranes.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0076464.g004