Specific Extracellular Matrix Remodeling Signature of Colon Hepatic Metastases
Figure 5
Functional annotation enrichment analysis of the 33-gene signature.
Gene Ontology terms significantly over-represented in the 33-gene signature were identified and plotted using ClueGO. A) The size of the nodes are inversely proportional to the pvalue in Fig. 5B. Line widths between GO terms are proportional to the kappa scores used to define the categories. B) Table giving the results of the ClueGO analysis. Nr: Number of genes in our 33-gene signature associated with the GO term.%: Percentage of the genes of the considered GO term presents in our signature. Pvalue: pvalue of the GO term, corrected for multiple testing. C) Relation between the GO annotations of the 11 “cell adhesion”-associated genes in Fig. 5B and GO:0007155 term. Black arrows: “is a”. Green arrows: “Positively regulates”.