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Grape Powder Intake Prevents Ovariectomy-Induced Anxiety-Like Behavior, Memory Impairment and High Blood Pressure in Female Wistar Rats

Figure 2

Analysis of marker of oxidative stress 8-isoprostane in CON, GP, OVX and OVX+GP rats.

8-isoprostane was measured in serum (A) and urine (B) using EIA kit. Bars are means ± SEM, n = 10 rats/group, P<0.05, (*) significantly different from control and GP and (#) significantly different from OVX. Group designations: CON (control; sham operated rats provided with tap water for drinking), GP (grape powder: sham operated rats provided with GP treated tap water for drinking), OVX (ovariectomized: rats subjected to surgical removal of ovaries and provided with tap water for drinking), OVX+GP (rats subjected to surgical removal of ovaries and provided with GP treated tap water for drinking).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0074522.g002