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Transglutaminase 2 Overexpression in Tumor Stroma Identifies Invasive Ductal Carcinomas of Breast at High Risk of Recurrence

Figure 5

Immunohistochemistry of N-epsilon gamma-glutamyl lysine amino residues in IDC tissues.

Panel shows (i) strong immunostaining for N-epsilon gamma-glutamyl lysine amino residues in both cytoplasm and stroma of IDC that showed strong TG2 staining; (ii) faint cytoplasmic but no staining for N-epsilon gamma-glutamyl lysine amino residues in stroma of IDCs that showed weak TG2 staining and (iii) negative control showing no TG2 immunostaining in either cytoplasm or stroma of IDCs (Original Magnification X400).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0074437.g005