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The Cooperative Roles of Two Kinetoplastid-Specific Kinesins in Cytokinesis and in Maintaining Cell Morphology in Bloodstream Trypanosomes

Figure 7

Electron microscopic analysis of TbKIN-C and TbKIN-D RNAi cells of the bloodstream form.

(A, B). A multi-nucleated TbKIN-C RNAi cell (A) and TbKIN-D RNAi cell (B). Arrows indicated the three flagella attached to the cell body. (C, D). TbKIN-C RNAi cells with an extremely large flagellar pocket. The arrow indicated the flagellum that has exited the flagellar pocket. The arrowheads in panel C pointed to the flagellar axoneme with a normal PFR inside the enlarged flagellar pocket, whereas the arrowheads in panel D pointed to the flagellar axoneme-like structure in the cytoplasm near the flagellar pocket. Insets are the enlarged view of the flagellum (panel C) and the flagellar axoneme-like structure. Bars: 0.4 µm.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0073869.g007