Fate Analysis of Adult Hippocampal Progenitors in a Murine Model of Fetal Alcohol Spectrum Disorder (FASD)
Figure 3
The neurogenic response to EE is blunted in FASD mice.
(A) Confocal images of hippocampal dentate: YFP immunofluorescence (green) and DAPI nuclear stain (blue). (B) Total number of YFP positive cell in dentate gyrus 10 weeks after TAM injection. Post hoc analysis revealed a significant increase in the total number YFP+ cells in Sac nestin-CreERT2/YFP mice, but not FASD nestin-CreERT2:YFP mice housed under environmental enrichment (*p<0.05, n = 8 mice per group).