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Geometry-Driven Cell Organization Determines Tissue Growths in Scaffold Pores: Consequences for Fibronectin Organization

Figure 6

Distribution of fibronectin and actin inside scaffold pores.

Actin (green) and fibronectin (red) intensity distribution from the pore center to the pore wall as extracted from histological images (Fig. 6a, npores = 4 for each category). From the maximum projection of the z-stack and the contoured pore, the Pearson coefficient for green and red channel colocalization was calculated. The whole intensity data range for each channel (0–255) was considered here (Fig. 6b, n = 5 for each category).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0073545.g006