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Discontinuous Patterns of Brain Activation in the Psychotherapy Process of Obsessive-Compulsive Disorder: Converging Results from Repeated fMRI and Daily Self-Reports

Figure 1

Expanded model of OCD pathophysiology.

A primary cognitive network (left) connects prefrontal and ventroanterior thalamic structures via dorsal striatal loops. A primary affective network (right) connects the posterior OFC and ventral parts of the ACC via ventral striatal loops and via limbic structures with the mediodorsal thalamus. The DLPFC interfaces with the parietal cortex and the cerebellum. (Modified according to [14], p. 264; [15], p. 541]).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0071863.g001