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Visualising Androgen Receptor Activity in Male and Female Mice

Figure 2

Androgen receptor reporter activity in transgenic mice.

(A), Bioluminescent imaging of male and female ARE-Luc and C57/Bl/6J wild type mice, injected with 150mg/kg luciferin substrate, and imaged with a CCCD camera after 10 minutes. Figure represents a greyscale photograph overlaid with a pseudocolour representation of bioluminescence; scale represents photons/sec/cm2.

(B), Luciferase enzymatic assays from tissue homogenates taken from ARE-Luc mice, normalised to protein content (Bradford assay). Male mice upper panel, female mice lower panel.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0071694.g002