In Vivo Monitoring of Angiogenesis Inhibition via Down-Regulation of Mir-21 in a VEGFR2-Luc Murine Breast Cancer Model Using Bioluminescent Imaging
Figure 6
The effect of antagomir-21 on tumor cell apoptosis.
Cell apoptosis was determined by TUNEL staining. (A) Green color is apoptotic cell stained by TUNEL; blue color is the cell nucleus stained by DAPI. Images were taken at a magnification of ×200. (B) Quantification of cell apoptosis from conditions in A. Data are expressed as mean ± SEM, n = 10, **P<0.01 vs control group.