Heparin-Binding Haemagglutinin, a New Tool for the Detection of Latent Mycobacterium tuberculosis Infection in Hemodialysis Patients
Figure 3
Positive nHBHA-IGRA results in QFT positive or negative HD patients.
PBMC freshly isolated from whole blood of 135 HD patients were incubated 24 hrs in presence of nHBHA (2 µg/ml) with 5 ng/ml IL-7, and the IFN-γ concentrations released in the cell cultures supernatants were measured by ELISA. Seventy-six subjects were nHBHA-IGRA positive. QFT was performed simultaneously and each dot represents a positive nHBHA-IGRA result (expressed in pg/ml) for single patient presenting either a positive QFT (QFT+ = 40) or a negative QFT (QFT− = 36). Horizontal bars represent the medians of the results.