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Correlation of Cutaneous Immunoreactants in Lesional Skin with the Serological Disorders and Disease Activity of Systemic Lupus Erythematosus

Figure 2

Deposit of immunoreactants along epidermal-dermal junction in lesional skin.

Skin sections were incubated with fluorescein isothiocyanate (FITC)-conjugated anti-human IgG, IgA, IgM, and C3 antibodies and visualized with a fluorescence microscope. A and B indicates the staining patterns of single immunoreactant detected from individual biopsy. The representative staining of the coexistence of two and three immunoreactants from two biopsies were shown in C and D, respectively. N.C, negative control without adding FITC-conjugated antibody.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0070983.g002