Skip to main content
Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Diabetic Mouse Model of Orthopaedic Implant-Related Staphylococcus Aureus Infection

Figure 5

Representative micro-CT images and bone mineral density (BMD).

Representative maximal intensity projection micro-CT images of the femurs with the pin implants in transverse (A, D) and sagittal (B, C, E, F) views in group I (upper panel) and group IV (lower panel). The upper panel shows the intact cortical bone profile without signs of infection (A), of the knee joint (B) and of the middle diaphysis section (C) in group I. The lower panel shows extensive bone loss, disruption of cortical integrity, cortical thinning and canal widening (D), acute septic arthritis of the knee joint (E) and bone loss in the middle diaphysis section (F) suggesting signs of established infection in group IV. The histogram shows a statistically significant difference in the BMD of group IV, as analyzed with one-way ANOVA and Bonferroni’s post-hoc (*P<0.05; n = 5).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0067628.g005