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Pharmacokinetics Study of Recombinant Hirudin in the Plasma of Rats Using Chromogenic Substrate, ELISA, and Radioisotope Assays

Figure 1

The recombinant hirudin concentration in plasma by CSA.

The concentration–time curve of recombinant hirudin in the plasma of rats that had been injected intravenously with 125I-recombinant hirudin, as determined by the chromogenic substrate assay. Each point represents mean±SD (n = 5).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0064336.g001